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Testing for Efficacy in Adaptive Clinical Trials with Enrichment

Adaptive design of clinical trials has attracted considerable interest because of its potential of reducing costs and saving time in the clinical development process. In this paper, we consider the problem of assessing the effectiveness of a test treatment over a control by a two-arm randomized clin...

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Detalhes bibliográficos
Publicado no:Stat Med
Main Authors: Wu, Samuel S., Tu, Yi-Hsuan, He, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362733/
https://ncbi.nlm.nih.gov/pubmed/24577792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.6127
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