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Adaptive enrichment trials: What are the benefits?

When planning a Phase III clinical trial, suppose a certain subset of patients is expected to respond particularly well to the new treatment. Adaptive enrichment designs make use of interim data in selecting the target population for the remainder of the trial, either continuing with the full popula...

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Detalhes bibliográficos
Publicado no:Stat Med
Main Authors: Burnett, Thomas, Jennison, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7839594/
https://ncbi.nlm.nih.gov/pubmed/33244786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.8797
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