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Adaptive enrichment trials: What are the benefits?

When planning a Phase III clinical trial, suppose a certain subset of patients is expected to respond particularly well to the new treatment. Adaptive enrichment designs make use of interim data in selecting the target population for the remainder of the trial, either continuing with the full popula...

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Dades bibliogràfiques
Publicat a:Stat Med
Autors principals: Burnett, Thomas, Jennison, Christopher
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7839594/
https://ncbi.nlm.nih.gov/pubmed/33244786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.8797
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