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Optimizing subgroup selection in two‐stage adaptive enrichment and umbrella designs
We design two‐stage confirmatory clinical trials that use adaptation to find the subgroup of patients who will benefit from a new treatment, testing for a treatment effect in each of two disjoint subgroups. Our proposal allows aspects of the trial, such as recruitment probabilities of each group, to...
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| Gepubliceerd in: | Stat Med |
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| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
John Wiley and Sons Inc.
2021
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8251960/ https://ncbi.nlm.nih.gov/pubmed/33783020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.8949 |
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