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Two-stage Adaptive Enrichment Design for Testing an Active Factor
We propose an adaptive enrichment approach to test an active factor, which is a factor whose effect is non-zero in at least one subpopulation. We implement a two stage play-the-winner design where all subjects in the second stage are enrolled from the subpopulation that has the highest observed effe...
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| Vydáno v: | J Biopharm Stat |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6881517/ https://ncbi.nlm.nih.gov/pubmed/31135263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543406.2019.1609015 |
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