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Two-Stage Adaptive Designs for Three-Treatment Bioequivalence Studies

Bioequivalence (BE) studies are most often conducted as crossover trials, and therefore establishing their required sample size necessitates specification of the within-person variance. Given that this specification is often difficult in practice, there has been great interest in recent years in the...

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Библиографические подробности
Опубликовано в: :Stat Biopharm Res
Главные авторы: Grayling, Michael J., Mander, Adrian P., Wason, James M.S.
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612189/
https://ncbi.nlm.nih.gov/pubmed/35003526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19466315.2019.1654911
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