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Melatonin enhances antioxidant molecules in the placenta, reduces secretion of soluble fms-like tyrosine kinase 1 (sFLT) from primary trophoblast but does not rescue endothelial dysfunction: An evaluation of its potential to treat preeclampsia

Preeclampsia is one of the most serious complications of pregnancy. Currently there are no medical treatments. Given placental oxidative stress may be an early trigger in the pathogenesis of preeclampsia, therapies that enhance antioxidant pathways have been proposed as treatments. Melatonin is a di...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hannan, Natalie J., Binder, Natalie K., Beard, Sally, Nguyen, Tuong-Vi, Kaitu’u-Lino, Tu’uhevaha J., Tong, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894956/
https://ncbi.nlm.nih.gov/pubmed/29641523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187082
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