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Resveratrol inhibits release of soluble fms-like tyrosine kinase (sFlt-1) and soluble endoglin and improves vascular dysfunction – implications as a preeclampsia treatment

Preeclampsia is a disease of pregnancy associated with placental oxidative stress, inflammation and elevated release of anti-angiogenic factors sFlt-1 and soluble endoglin. These placental factors cause generalized maternal endothelial dysfunction. There are no treatments to halt disease progression...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Hannan, Natalie J., Brownfoot, Fiona C., Cannon, Ping, Deo, Minh, Beard, Sally, Nguyen, Tuong V., Palmer, Kirsten R., Tong, Stephen, Kaitu’u-Lino, Tu’uhevaha J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5431923/
https://ncbi.nlm.nih.gov/pubmed/28500309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01993-w
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