ELABELA/APELA Levels Are Not Decreased in the Maternal Circulation or Placenta among Women with Preeclampsia

The genetic deletion of apelin receptor early endogenous ligand (Elabela; official name APELA) produces a preeclampsia-like phenotype in mice. However, evidence linking ELABELA with human disease is lacking. Therefore, we measured placental mRNA and circulating ELABELA in human samples. ELABELA mRNA...

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Udgivet i:Am J Pathol
Main Authors: Pritchard, Natasha, Kaitu'u-Lino, Tu'uhevaha J., Gong, Sungsam, Dopierala, Justyna, Smith, Gordon C.S., Charnock-Jones, D. Stephen, Tong, Stephen
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063996/
https://ncbi.nlm.nih.gov/pubmed/29803833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2018.04.008
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