Circulating GATA2 mRNA is decreased among women destined to develop preeclampsia and may be of endothelial origin

Preeclampsia is a pregnancy complication associated with elevated placental secretion of anti-angiogenic factors, maternal endothelial dysfunction and organ injury. GATA2 is a transcription factor expressed in the endothelium which regulates vascular homeostasis by controlling transcription of genes...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Whigham, Carole-Anne, MacDonald, Teresa M., Walker, Susan P., Pritchard, Natasha, Hannan, Natalie J., Cannon, Ping, Nguyen, Tuong Vi, Hastie, Roxanne, Tong, Stephen, Kaitu’u-Lino, Tu’uhevaha J.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338784/
https://ncbi.nlm.nih.gov/pubmed/30659233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36645-0
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