Trophoblast-Targeted Nanomedicine Modulates Placental sFLT1 for Preeclampsia Treatment

The overexpressed soluble fms-like tyrosine kinase 1 (sFLT-1) in placenta is considered to be a potential therapeutic target for preeclampsia (PE). How to achieve efficient intervention of sFLT1 expression in the placenta is an urgent problem to be solved. PEG-PLA nanoparticle generated by double-em...

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Bibliographic Details
Published in:Front Bioeng Biotechnol
Main Authors: Li, Lei, Yang, Huijun, Chen, Pengzheng, Xin, Tao, Zhou, Qian, Wei, Dan, Zhang, Yanan, Wang, Shan
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Bioengineering and Biotechnology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7026029/
https://ncbi.nlm.nih.gov/pubmed/32117942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00064
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