RNAi Modulation of Placental sFLT1 for the Treatment of Preeclampsia.

Preeclampsia (PE) is a placentally-induced hypertensive disorder of pregnancy that is associated with significant morbidity and mortality to mothers and fetuses. Clinical manifestations of preterm PE result from excess circulating soluble vascular endothelial growth factor receptor FLT1 (sFLT1 or sV...

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Detalhes bibliográficos
Publicado no:Nat Biotechnol
Main Authors: Turanov, Anton A., Lo, Agnes, Hassler, Matthew R., Makris, Angela, Ashar-Patel, Ami, Alterman, Julia F., Coles, Andrew H., Haraszti, Reka A., Roux, Loic, Godinho, Bruno MDC, Echeverria, Dimas, Pears, Suzanne, Iliopoulos, Jim, Shanmugalingam, Renuka, Ogle, Robert, Zsengeller, Zsuzsanna K., Hennessy, Annemarie, Karumanchi, S. Ananth, Moore, Melissa J., Khvorova, Anastasia
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526074/
https://ncbi.nlm.nih.gov/pubmed/30451990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.4297
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