Transcriptionally active syncytial aggregates in the maternal circulation may contribute to circulating sFlt1 in preeclampsia

The cardinal manifestations of the pregnancy-specific disorder preeclampsia, new-onset hypertension and proteinuria that resolve with placental delivery, have been linked to an extracellular protein made by the placenta, sFlt1 (soluble fms-like tyrosine kinase 1), that injures the maternal vasculatu...

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Auteurs principaux: Rajakumar, Augustine, Cerdeira, Ana Sofia, Rana, Sarosh, Zsengeller, Zsuzsanna, Edmunds, Lia, Jeyabalan, Arun, Hubel, Carl A., Stillman, Issac E., Parikh, Samir M., Karumanchi, S. Ananth
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319764/
https://ncbi.nlm.nih.gov/pubmed/22215706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.111.182170
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