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Intracellular nucleic acid sensing triggers necroptosis through synergistic type-I interferon and TNF signaling

The sensing of viral nucleic acids within the cytosol is essential for the induction of innate immune responses following infection. However, this sensing occurs within cells that have already been infected. The death of infected cells can be beneficial to the host by eliminating the virus’s replica...

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書目詳細資料
發表在:J Immunol
Main Authors: Brault, Michelle, Olsen, Tayla M., Martinez, Jennifer, Stetson, Daniel B., Oberst, Andrew
格式: Artigo
語言:Inglês
出版: 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5893403/
https://ncbi.nlm.nih.gov/pubmed/29540580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701492
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