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Intracellular nucleic acid sensing triggers necroptosis through synergistic type-I interferon and TNF signaling
The sensing of viral nucleic acids within the cytosol is essential for the induction of innate immune responses following infection. However, this sensing occurs within cells that have already been infected. The death of infected cells can be beneficial to the host by eliminating the virus’s replica...
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| Publicado en: | J Immunol |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5893403/ https://ncbi.nlm.nih.gov/pubmed/29540580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701492 |
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