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Intracellular Nucleic Acid Detection in Autoimmunity

Protective immune responses to viral infection are initiated by innate immune sensors that survey extracellular and intracellular space for foreign nucleic acids. The existence of these sensors raises fundamental questions about self/non-self discrimination because of the abundance of self-DNA and s...

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Detalhes bibliográficos
Publicado no:Annu Rev Immunol
Main Authors: Crowl, John T., Gray, Elizabeth E., Pestal, Kathleen, Volkman, Hannah, Stetson, Daniel B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435037/
https://ncbi.nlm.nih.gov/pubmed/28142323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-immunol-051116-052331
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