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The enemy within: endogenous retroelements and autoimmune disease
Inappropriate or chronic detection of self nucleic acids by the innate immune system underlies a number of human autoimmune diseases. We discuss here an unexpected source of endogenous immunostimulatory nucleic acids: the reverse transcribed cDNAs of endogenous retroelements. The interplay between i...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4131434/ https://ncbi.nlm.nih.gov/pubmed/24747712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2872 |
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