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The enemy within: endogenous retroelements and autoimmune disease

Inappropriate or chronic detection of self nucleic acids by the innate immune system underlies a number of human autoimmune diseases. We discuss here an unexpected source of endogenous immunostimulatory nucleic acids: the reverse transcribed cDNAs of endogenous retroelements. The interplay between i...

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Main Authors: Volkman, Hannah E., Stetson, Daniel B.
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131434/
https://ncbi.nlm.nih.gov/pubmed/24747712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2872
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