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Intracellular nucleic acid sensing triggers necroptosis through synergistic type-I interferon and TNF signaling

The sensing of viral nucleic acids within the cytosol is essential for the induction of innate immune responses following infection. However, this sensing occurs within cells that have already been infected. The death of infected cells can be beneficial to the host by eliminating the virus’s replica...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Brault, Michelle, Olsen, Tayla M., Martinez, Jennifer, Stetson, Daniel B., Oberst, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5893403/
https://ncbi.nlm.nih.gov/pubmed/29540580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701492
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