Nitric oxide-mediated posttranslational modifications control neurotransmitter release by modulating complexin farnesylation and enhancing its clamping ability

Nitric oxide (NO) regulates neuronal function and thus is critical for tuning neuronal communication. Mechanisms by which NO modulates protein function and interaction include posttranslational modifications (PTMs) such as S-nitrosylation. Importantly, cross signaling between S-nitrosylation and pre...

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Pubblicato in:PLoS Biol
Autori principali: Robinson, Susan W., Bourgognon, Julie-Myrtille, Spiers, Jereme G., Breda, Carlo, Campesan, Susanna, Butcher, Adrian, Mallucci, Giovanna R., Dinsdale, David, Morone, Nobuhiro, Mistry, Raj, Smith, Tim M., Guerra-Martin, Maria, Challiss, R. A. John, Giorgini, Flaviano, Steinert, Joern R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890968/
https://ncbi.nlm.nih.gov/pubmed/29630591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2003611
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