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Alterations in neuronal metabolism contribute to the pathogenesis of prion disease

Neurodegenerative conditions are characterised by a progressive loss of neurons, which is believed to be initiated by misfolded protein aggregations. During this time period, many physiological and metabolomic alterations and changes in gene expression contribute to the decline in neuronal function....

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Bourgognon, Julie-Myrtille, Spiers, Jereme G., Scheiblich, Hannah, Antonov, Alexey, Bradley, Sophie J., Tobin, Andrew B., Steinert, Joern R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6113283/
https://ncbi.nlm.nih.gov/pubmed/29915278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0148-x
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