Genes contributing to prion pathogenesis

Prion diseases are caused by conversion of a normally folded, nonpathogenic isoform of the prion protein (PrP(C)) to a misfolded, pathogenic isoform (PrP(Sc)). Prion inoculation experiments in mice expressing homologous PrP(C) molecules on different genetic backgrounds displayed different incubation...

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Detalhes bibliográficos
Main Authors: Tamgüney, Gültekin, Giles, Kurt, Glidden, David V., Lessard, Pierre, Wille, Holger, Tremblay, Patrick, Groth, Darlene F., Yehiely, Fruma, Korth, Carsten, Moore, Richard C., Tatzelt, Jörg, Rubenstein, Eric, Boucheix, Claude, Yang, Xiaoping, Stanley, Pamela, Lisanti, Michael P., Dwek, Raymond A., Rudd, Pauline M., Moskovitz, Jackob, Epstein, Charles J., Cruz, Tracey Dawson, Kuziel, William A., Maeda, Nobuyo, Sap, Jan, Ashe, Karen Hsiao, Carlson, George A., Tesseur, Ina, Wyss-Coray, Tony, Mucke, Lennart, Weisgraber, Karl H., Mahley, Robert W., Cohen, Fred E., Prusiner, Stanley B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828448/
https://ncbi.nlm.nih.gov/pubmed/18559949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.2008/001255-0
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