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Genes contributing to prion pathogenesis
Prion diseases are caused by conversion of a normally folded, nonpathogenic isoform of the prion protein (PrP(C)) to a misfolded, pathogenic isoform (PrP(Sc)). Prion inoculation experiments in mice expressing homologous PrP(C) molecules on different genetic backgrounds displayed different incubation...
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| Asıl Yazarlar: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2008
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2828448/ https://ncbi.nlm.nih.gov/pubmed/18559949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.2008/001255-0 |
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