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Metformin targets central carbon metabolism and reveals mitochondrial requirements in human cancers
Repurposing metformin for cancer therapy is attractive due to its safety profile, epidemiological evidence, and encouraging data from human clinical trials. Although it is known to systemically affect glucose metabolism in liver, muscle, gut, and other tissues, the molecular determinants that predic...
Tallennettuna:
| Julkaisussa: | Cell Metab |
|---|---|
| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2016
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5889952/ https://ncbi.nlm.nih.gov/pubmed/27746051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.09.005 |
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