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Molecular Pathways: Trafficking of Metabolic Resources in the Tumor Microenvironment

A new model of tumor metabolism is proposed that describes how the complementary metabolic functions of the local stroma and the tumor cells contribute to cancer progression. Cancer cells alter the metabolism of cancer-associated fibroblasts to obtain lactate and amino acids, which are utilized for...

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Dettagli Bibliografici
Pubblicato in:Clin Cancer Res
Autori principali: Romero, Iris L., Mukherjee, Abir, Kenny, Hilary A., Litchfield, Lacey M., Lengyel, Ernst
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333734/
https://ncbi.nlm.nih.gov/pubmed/25691772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2198
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