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Molecular Pathways: Trafficking of Metabolic Resources in the Tumor Microenvironment

A new model of tumor metabolism is proposed that describes how the complementary metabolic functions of the local stroma and the tumor cells contribute to cancer progression. Cancer cells alter the metabolism of cancer-associated fibroblasts to obtain lactate and amino acids, which are utilized for...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Romero, Iris L., Mukherjee, Abir, Kenny, Hilary A., Litchfield, Lacey M., Lengyel, Ernst
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333734/
https://ncbi.nlm.nih.gov/pubmed/25691772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2198
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