Hyperglycemia-induced metabolic compensation inhibits metformin sensitivity in ovarian cancer

Increasing interest in repurposing the diabetic medication metformin for cancer treatment has raised important questions about the translation of promising preclinical findings to therapeutic efficacy, especially in non-diabetic patients. A significant limitation of the findings to date is the use o...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Litchfield, Lacey M., Mukherjee, Abir, Eckert, Mark A., Johnson, Alyssa, Mills, Kathryn A., Pan, Shawn, Shridhar, Viji, Lengyel, Ernst, Romero, Iris L.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695136/
https://ncbi.nlm.nih.gov/pubmed/26172303
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