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DNA sliding in nucleosomes via twist defect propagation revealed by molecular simulations

While nucleosomes are highly stable structures as fundamental units of chromatin, they also slide along the DNA, either spontaneously or by active remodelers. Here, we investigate the microscopic mechanisms of nucleosome sliding by multiscale molecular simulations, characterizing how the screw-like...

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Библиографические подробности
Опубликовано в: :Nucleic Acids Res
Главные авторы: Brandani, Giovanni B, Niina, Toru, Tan, Cheng, Takada, Shoji
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887990/
https://ncbi.nlm.nih.gov/pubmed/29506273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky158
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