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DNA sliding in nucleosomes via twist defect propagation revealed by molecular simulations

While nucleosomes are highly stable structures as fundamental units of chromatin, they also slide along the DNA, either spontaneously or by active remodelers. Here, we investigate the microscopic mechanisms of nucleosome sliding by multiscale molecular simulations, characterizing how the screw-like...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Brandani, Giovanni B, Niina, Toru, Tan, Cheng, Takada, Shoji
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887990/
https://ncbi.nlm.nih.gov/pubmed/29506273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky158
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