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Partial Unwrapping and Histone Tail Dynamics in Nucleosome Revealed by Coarse-Grained Molecular Simulations

Nucleosomes, basic units of chromatin, are known to show spontaneous DNA unwrapping dynamics that are crucial for transcriptional activation, but its structural details are yet to be elucidated. Here, employing a coarse-grained molecular model that captures residue-level structural details up to his...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:PLoS Comput Biol
Päätekijät: Kenzaki, Hiroo, Takada, Shoji
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532510/
https://ncbi.nlm.nih.gov/pubmed/26262925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004443
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