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Histone acetylation dependent energy landscapes in tri-nucleosome revealed by residue-resolved molecular simulations

Histone tail acetylation is a key epigenetic marker that tends to open chromatin folding and activate transcription. Despite intensive studies, precise roles of individual lysine acetylation in chromatin folding have only been poorly understood. Here, we revealed structural dynamics of tri-nucleosom...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chang, Le, Takada, Shoji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048180/
https://ncbi.nlm.nih.gov/pubmed/27698366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34441
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