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Histone dynamics mediate DNA unwrapping and sliding in nucleosomes
Nucleosomes are elementary building blocks of chromatin in eukaryotes. They tightly wrap ∼147 DNA base pairs around an octamer of histone proteins. How nucleosome structural dynamics affect genome functioning is not completely clear. Here we report all-atom molecular dynamics simulations of nucleoso...
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| I publikationen: | Nat Commun |
|---|---|
| Huvudupphovsmän: | , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Nature Publishing Group UK
2021
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8062685/ https://ncbi.nlm.nih.gov/pubmed/33888707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22636-9 |
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