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Coupling between histone conformations and DNA geometry in nucleosomes on a microsecond timescale: atomistic insights into nucleosome functions
An octamer of histone proteins wraps about 200 base pairs of DNA into two super-helical turns to form nucleosomes found in chromatin. Although the static structure of the nucleosomal core particle has been solved, details of the dynamic interactions between histones and DNA remain elusive. We perfor...
Gardado en:
| Publicado en: | J Mol Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4738025/ https://ncbi.nlm.nih.gov/pubmed/26699921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.12.004 |
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