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Hydroxyl-radical footprinting combined with molecular modeling identifies unique features of DNA conformation and nucleosome positioning

Nucleosomes are the most abundant protein–DNA complexes in eukaryotes that provide compaction of genomic DNA and are implicated in regulation of transcription, DNA replication and repair. The details of DNA positioning on the nucleosome and the DNA conformation can provide key regulatory signals. Hy...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Shaytan, Alexey K., Xiao, Hua, Armeev, Grigoriy A., Wu, Carl, Landsman, David, Panchenko, Anna R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765820/
https://ncbi.nlm.nih.gov/pubmed/28934480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx616
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