Dynamic unwrapping of nucleosomes by HsRAD51 that includes sliding and rotational motion of histone octamers

Wrapping of genomic DNA into nucleosomes poses thermodynamic and kinetic barriers to biological processes such as replication, transcription, repair and recombination. Previous biochemical studies have demonstrated that in the presence of adenosine triphosphate (ATP) the human RAD51 (HsRAD51) recomb...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Senavirathne, Gayan, Mahto, Santosh K., Hanne, Jeungphill, O'Brian, Daniel, Fishel, Richard
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
Subjects:
Gene regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314800/
https://ncbi.nlm.nih.gov/pubmed/27738136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw920
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