Regulation of the nucleosome unwrapping rate controls DNA accessibility

Eukaryotic genomes are repetitively wrapped into nucleosomes that then regulate access of transcription and DNA repair complexes to DNA. The mechanisms that regulate extrinsic protein interactions within nucleosomes are unresolved. We demonstrate that modulation of the nucleosome unwrapping rate reg...

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Detalhes bibliográficos
Main Authors: North, Justin A., Shimko, John C., Javaid, Sarah, Mooney, Alex M., Shoffner, Matthew A., Rose, Sean D., Bundschuh, Ralf, Fishel, Richard, Ottesen, Jennifer J., Poirier, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Gene Regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488218/
https://ncbi.nlm.nih.gov/pubmed/22965129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks747
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