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DNA sliding in nucleosomes via twist defect propagation revealed by molecular simulations

While nucleosomes are highly stable structures as fundamental units of chromatin, they also slide along the DNA, either spontaneously or by active remodelers. Here, we investigate the microscopic mechanisms of nucleosome sliding by multiscale molecular simulations, characterizing how the screw-like...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Brandani, Giovanni B, Niina, Toru, Tan, Cheng, Takada, Shoji
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887990/
https://ncbi.nlm.nih.gov/pubmed/29506273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky158
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