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DNA sliding in nucleosomes via twist defect propagation revealed by molecular simulations
While nucleosomes are highly stable structures as fundamental units of chromatin, they also slide along the DNA, either spontaneously or by active remodelers. Here, we investigate the microscopic mechanisms of nucleosome sliding by multiscale molecular simulations, characterizing how the screw-like...
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| Publié dans: | Nucleic Acids Res |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5887990/ https://ncbi.nlm.nih.gov/pubmed/29506273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky158 |
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