Regenerative proliferation of differentiated cells by mTORC1‐dependent paligenosis

In 1900, Adami speculated that a sequence of context‐independent energetic and structural changes governed the reversion of differentiated cells to a proliferative, regenerative state. Accordingly, we show here that differentiated cells in diverse organs become proliferative via a shared program. Me...

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Pubblicato in:EMBO J
Autori principali: Willet, Spencer G, Lewis, Mark A, Miao, Zhi‐Feng, Liu, Dengqun, Radyk, Megan D, Cunningham, Rebecca L, Burclaff, Joseph, Sibbel, Greg, Lo, Hei‐Yong G, Blanc, Valerie, Davidson, Nicholas O, Wang, Zhen‐Ning, Mills, Jason C
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881627/
https://ncbi.nlm.nih.gov/pubmed/29467218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201798311
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