Regenerative proliferation of differentiated cells by mTORC1‐dependent paligenosis

In 1900, Adami speculated that a sequence of context‐independent energetic and structural changes governed the reversion of differentiated cells to a proliferative, regenerative state. Accordingly, we show here that differentiated cells in diverse organs become proliferative via a shared program. Me...

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Vydáno v:EMBO J
Hlavní autoři: Willet, Spencer G, Lewis, Mark A, Miao, Zhi‐Feng, Liu, Dengqun, Radyk, Megan D, Cunningham, Rebecca L, Burclaff, Joseph, Sibbel, Greg, Lo, Hei‐Yong G, Blanc, Valerie, Davidson, Nicholas O, Wang, Zhen‐Ning, Mills, Jason C
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881627/
https://ncbi.nlm.nih.gov/pubmed/29467218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201798311
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