Regenerative proliferation of differentiated cells by mTORC1‐dependent paligenosis

In 1900, Adami speculated that a sequence of context‐independent energetic and structural changes governed the reversion of differentiated cells to a proliferative, regenerative state. Accordingly, we show here that differentiated cells in diverse organs become proliferative via a shared program. Me...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Willet, Spencer G, Lewis, Mark A, Miao, Zhi‐Feng, Liu, Dengqun, Radyk, Megan D, Cunningham, Rebecca L, Burclaff, Joseph, Sibbel, Greg, Lo, Hei‐Yong G, Blanc, Valerie, Davidson, Nicholas O, Wang, Zhen‐Ning, Mills, Jason C
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881627/
https://ncbi.nlm.nih.gov/pubmed/29467218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201798311
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