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Specifically bound lambda repressor dimers promote adjacent non-specific binding

Genetic switches frequently include DNA loops secured by proteins. Recent studies of the lambda bacteriophage repressor (CI), showed that this arrangement in which the protein links two sets of three operators separated by approximately 2.3 kbp, optimizes both the stability and dynamics of DNA loops...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Sarkar-Banerjee, Suparna, Goyal, Sachin, Gao, Ning, Mack, John, Thompson, Benito, Dunlap, David, Chattopadhyay, Krishnananda, Finzi, Laura
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880393/
https://ncbi.nlm.nih.gov/pubmed/29608611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194930
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