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The Effect of Nonspecific Binding of Lambda Repressor on DNA Looping Dynamics

The λ repressor (CI) protein-induced DNA loop maintains stable lysogeny, yet allows efficient switching to lysis. Herein, the kinetics of loop formation and breakdown has been characterized at various concentrations of protein using tethered particle microscopy and a novel, to our knowledge, method...

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Detalhes bibliográficos
Main Authors: Manzo, Carlo, Zurla, Chiara, Dunlap, David D., Finzi, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475330/
https://ncbi.nlm.nih.gov/pubmed/23083719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.09.006
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