Direct demonstration and quantification of long-range DNA looping by the λ bacteriophage repressor

Recently, it was proposed that DNA looping by the λ repressor (CI protein) strengthens repression of lytic genes during lysogeny and simultaneously ensures efficient switching to lysis. To investigate this hypothesis, tethered particle motion experiments were performed and dynamic CI-mediated loopin...

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Hlavní autoři: Zurla, Chiara, Manzo, Carlo, Dunlap, David, Lewis, Dale E. A., Adhya, Sankar, Finzi, Laura
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
Structural Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685085/
https://ncbi.nlm.nih.gov/pubmed/19276206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp134
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