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DNA supercoiling: A regulatory signal for the λ repressor

Topoisomerases, polymerases, and the chirality introduced by the binding of histones or nucleoid-associated proteins affect DNA supercoiling in vivo. However, supercoiling is not just a by-product of DNA metabolism. Supercoiling is an indicator of cell health, it modifies the accessibility of chroma...

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Main Authors: Ding, Yue, Manzo, Carlo, Fulcrand, Geraldine, Leng, Fenfei, Dunlap, David, Finzi, Laura
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217475/
https://ncbi.nlm.nih.gov/pubmed/25319264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320644111
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