The Effect of Nonspecific Binding of Lambda Repressor on DNA Looping Dynamics

The λ repressor (CI) protein-induced DNA loop maintains stable lysogeny, yet allows efficient switching to lysis. Herein, the kinetics of loop formation and breakdown has been characterized at various concentrations of protein using tethered particle microscopy and a novel, to our knowledge, method...

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Bibliographic Details
Main Authors: Manzo, Carlo, Zurla, Chiara, Dunlap, David D., Finzi, Laura
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2012
Subjects:
Proteins and Nucleic Acids
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475330/
https://ncbi.nlm.nih.gov/pubmed/23083719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.09.006
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