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The Effect of Nonspecific Binding of Lambda Repressor on DNA Looping Dynamics

The λ repressor (CI) protein-induced DNA loop maintains stable lysogeny, yet allows efficient switching to lysis. Herein, the kinetics of loop formation and breakdown has been characterized at various concentrations of protein using tethered particle microscopy and a novel, to our knowledge, method...

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Hlavní autoři: Manzo, Carlo, Zurla, Chiara, Dunlap, David D., Finzi, Laura
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475330/
https://ncbi.nlm.nih.gov/pubmed/23083719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.09.006
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