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Stretching DNA to quantify non-specific protein binding

Non-specific binding of regulatory proteins to DNA can be an important mechanism for target search and storage. This seems to be the case for the lambda repressor protein (CI), which maintains lysogeny after infection of E. coli. CI binds specifically at two distant regions along the viral genome an...

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Detalhes bibliográficos
Main Authors: Goyal, Sachin, Fountain, Chandler, Dunlap, David, Family, Fereydoon, Finzi, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653181/
https://ncbi.nlm.nih.gov/pubmed/23005450
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