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Stretching DNA to quantify non-specific protein binding

Non-specific binding of regulatory proteins to DNA can be an important mechanism for target search and storage. This seems to be the case for the lambda repressor protein (CI), which maintains lysogeny after infection of E. coli. CI binds specifically at two distant regions along the viral genome an...

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Autors principals: Goyal, Sachin, Fountain, Chandler, Dunlap, David, Family, Fereydoon, Finzi, Laura
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653181/
https://ncbi.nlm.nih.gov/pubmed/23005450
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