Specifically bound lambda repressor dimers promote adjacent non-specific binding

Genetic switches frequently include DNA loops secured by proteins. Recent studies of the lambda bacteriophage repressor (CI), showed that this arrangement in which the protein links two sets of three operators separated by approximately 2.3 kbp, optimizes both the stability and dynamics of DNA loops...

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Udgivet i:PLoS One
Main Authors: Sarkar-Banerjee, Suparna, Goyal, Sachin, Gao, Ning, Mack, John, Thompson, Benito, Dunlap, David, Chattopadhyay, Krishnananda, Finzi, Laura
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880393/
https://ncbi.nlm.nih.gov/pubmed/29608611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194930
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