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Chemo-enzymatic synthesis of selectively (13)C/(15)N-labeled RNA for NMR structural and dynamics studies
RNAs are an important class of cellular regulatory elements, and they are well characterized by X-ray crystallography and nuclear magnetic resonance (NMR) spectroscopy in their folded or bound states. However, the apo or unfolded states are more difficult to characterize by either method. Particular...
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| Опубликовано в: : | Methods Enzymol |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5879494/ https://ncbi.nlm.nih.gov/pubmed/25432748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-801122-5.00007-6 |
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