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Chemo-enzymatic synthesis of selectively (13)C/(15)N-labeled RNA for NMR structural and dynamics studies

RNAs are an important class of cellular regulatory elements, and they are well characterized by X-ray crystallography and nuclear magnetic resonance (NMR) spectroscopy in their folded or bound states. However, the apo or unfolded states are more difficult to characterize by either method. Particular...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Methods Enzymol
Prif Awduron: Alvarado, Luigi J., Longhini, Andrew P., LeBlanc, Regan M., Chen, Bin, Kreutz, Christoph, Dayie, T. Kwaku
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5879494/
https://ncbi.nlm.nih.gov/pubmed/25432748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-801122-5.00007-6
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