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Asymmetry of (13)C labeled 3-pyruvate affords improved site specific labeling of RNA for NMR spectroscopy

Selective isotopic labeling provides an unparalleled window within which to study the structure and dynamics of RNAs by high resolution NMR spectroscopy. Unlike commonly used carbon sources, the asymmetry of (13)C-labeled pyruvate provides selective labeling in both the ribose and base moieties of n...

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Bibliografiske detaljer
Main Authors: Thakur, Chandar S., Dayie, T. Kwaku
Format: Artigo
Sprog:Inglês
Udgivet: Springer Netherlands 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222825/
https://ncbi.nlm.nih.gov/pubmed/22038649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-011-9581-6
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