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Asymmetry of (13)C labeled 3-pyruvate affords improved site specific labeling of RNA for NMR spectroscopy

Selective isotopic labeling provides an unparalleled window within which to study the structure and dynamics of RNAs by high resolution NMR spectroscopy. Unlike commonly used carbon sources, the asymmetry of (13)C-labeled pyruvate provides selective labeling in both the ribose and base moieties of n...

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Bibliografische gegevens
Hoofdauteurs: Thakur, Chandar S., Dayie, T. Kwaku
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer Netherlands 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222825/
https://ncbi.nlm.nih.gov/pubmed/22038649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-011-9581-6
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