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Drugs Being Eliminated via the Same Pathway Will Not Always Require Similar Pediatric Dose Adjustments
For scaling drug plasma clearance (CLp) from adults to children, extrapolations of population pharmacokinetic (PopPK) covariate models between drugs sharing an elimination pathway have enabled accelerated development of pediatric models and dosing recommendations. This study aims at identifying cond...
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| 出版年: | CPT Pharmacometrics Syst Pharmacol |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5869561/ https://ncbi.nlm.nih.gov/pubmed/29399979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12273 |
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